The publication of Paul Rothemund’s paper on DNA origami (Nature, March 16, 2006) marked a turning point in DNA nanotechnology, enabling unprecedented control over designed molecular structures.  This symposium is intended to honor Paul Rothemund’s contribution to the field and to survey the spectrum of inspiring research that it has lead to — and perhaps to give a glimmer of what is yet to come.

Talks will cover DNA nanotechnology, self-assembly and pattern formation, computational algorithms and software for origami design and analysis, applications in biology and biomedicine, applications in quantum physics, molecular motors and mechanical devices, biophysics and thermodynamics and kinetics, and more.

Organizing Committee and Program Committee

Ebbe Sloth Andersen, Aarhus University
Shawn Douglas, University of California San Francisco
Richard Murray, Caltech
Niles Pierce, Caltech
Lulu Qian, Caltech
Ned Seeman, New York University
William Shih, Harvard
Fritz Simmel, Technical University Munich
Erik Winfree (chair), Caltech

Surrounding the Symposium...

Ten Years of DNA Origami
          Caltech Press Release
DNA Origami: Twisting the Basis of Life in New Directions
          The Kavli Foundation
DNA Origami: Folded DNA as a Building Material for Molecular Devices
          Paul Rothemund's Earnest C. Watson Lecture


Participation as a speaker is by invitation only. The workshop format will include 24 talks and ample time for informal discussion during the (optional) Monday banquet and during an (optional) hike on Wednesday. 


All are welcome, but please register online; venue seating is limited. There is a nominal $50 fee for the (optional) banquet; please pay by credit card on the registration site if you wish to come to the banquet. Paul Rothemund will be the banquet speaker. UPDATE: Registration is now closed. Unregistered individuals may still attend talks if seating is available.

Please email questions to lucinda@caltech.edu.

DNA Origami News & Reviews

Nanostructures: The manifold faces of DNA, Nature 2006
When art and science meet, nanoscale smiley faces abound, Sci Am 2008
Folding our way to a revolution, SEED 2009
Bioengineering: What to make with DNA origami, Nature 2010
Returning to the fold, Nature Materials 2016
Practical DNA, Nature 2016
Ten years of DNA origami, a Nature journal video 2016

DNA origami: A history and current perspective, Curr Opin Chem Biol 2010
DNA origami: Fold, stick, and beyond, Nanoscale 2010
A primer to scaffolded DNA origami, Nature Methods 2011
DNA origami: A quantum leap for self-assembly..., Chem Soc Rev 2011
DNA origami: The art of folding DNA, Angew Chem 2012
Single-molecule analysis using DNA origami, Angew Chem 2012
Overview of DNA origami for molecular self-assembly, WIREs N+N 2013
Beyond DNA origami: The unfolding prospects..., WIREs N+N 2013
DNA origami technology for biomaterials applications, Biomater Sci 2013
Nanopores formed by DNA origami: A review, FEBS Letters 2014
DNA origami nanopores: Developments, challenges..., Nanoscale 2014
DNA origami: Folded DNA-nanodevices..., Adv Mater 2016
Beyond the fold: Emerging biological applications..., ChemBioChem 2016